For strategies, I'd run everyone in waves.
Doomreavers
Jack(s)
Uhlans
Doomreavers block spells and are nasty pieces of work--let them soak shots up and rip apart anything they can. Just be careful with facings in combat so they don't just kill each other.
Sorscha casts def. spells on them until she can wind rush up for the feat popping. Kodiak Vents steam on the way up and goes 'jack hunting, and Uhlans (which can come in from the flank, they're fast enough) knock stuff down (especially the 'caster/'lock) so Sorscha can move in for the kill.
Destroyer moves up and pops as many shots off as possible before counterassaulting/wading into melee.
Butcher won't get Icy Gaze, but the same kind of strategy applies: run up and whack stuff.
You have NO way of dealing with incorporeals, fast lists, or range-heavy lists (other than hitting them very, very hard). Just bear that in mind. Cryx and Legion will make your gaming very, very painful, as both lists are very fast, and the 'caster/lock can hide in the back, out of the reach of your stompies very easily. Menoth swarm will be something of a headache (obviously not an issue at 350), and Irusk and Haley will give any list fits (Inhospitable Ground and Temporal Barrier, respectively), even the Doom Reavers, as they're not targeted by those spells.
In addition to the previous suggestions (that is, MOWDC, widowmakers and mortar), consider Greylords Ternion, Eyriss, and Lady Aiyana/Master Holt. Those three support units/solos are VERY helpful for dealing with things that can't be hit well otherwise, be they magical, incorporeal, high def/arm, or tough/lots of wounds.
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