Looking a the ASTRA MILITARUM powers, many of them have the text: "if manifested, select an enemy unit within X" " Which implies that I can manifest the power, before choosing a target, and if there are not targets in range, the power was still 'manifested'.
(At least with these powers) you roll to manifest, before choosing a target, so you can still try if there are no valid targets within range; it will just do nothing. I'm not certain of other powers, that's the only Codex I have.
The rulebook does not specify that you have to choose a target before manifesting (though I suspect many players play it that way).
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