I've been dabbling with this.
You absolutely can do it with an airbrush, it works very well. Probably better than with a rattle can, as you have better accuracy and control.
If you're doing it with an airbrush you shouldn't lose any detail at all. You might though if you're doing multiple thick coats with a can.
If you're then going to do a completely opaque base coat, then yeah you are not going to see any benefit. It works best with inks / contrast-style paints. In a nutshell, it's like slapchop but without the drybrushing...
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