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I think it's up to you to decide whether you're happy inhaling what doesn't get filtered. The filter only filters particulates, and it doesn't do a particularly good job of that anyway on most of the cheap spray booths I've seen.
You can also wear a mask, but that doesn't protect your eyes. I had a friend who decided to spray acrylic primer on car body panels in a booth when the fan wasn't working, he wore a mask but afterwards the whites of his eyes were faintly coloured the same colour as the primer. That's obviously a super extreme example, but it's worth being aware that your eyes are capable of absorbing stuff.
Even if you had the hose on it leading to a window, I've found my cheap spray booth barely pulls hard enough to suck the atomised cloud out of the booth as fast as I'm spraying it into the booth, and if there's a wind coming at the window the booth's fan will not win and it'll push air backwards through the fan. I replaced the fan in mine with something much beefier, though I was using mine to spray enamels and lacquers so I wanted that stuff out the window rather than relying on my mask.
You can look up the SDS of paints you're working with, they're definitely not all created equal, some have chemicals that haven't been sufficiently tested to know if they're safe, some might have cadmium or cobalt or known unsafe things (though that's getting increasingly rare, if you have an older set of paints it might have that stuff in it and not even tell you).
Personally I've always felt the best approach to safety is to not screw around and just get the cloud of dust/paint/vapours away from me so I don't have to worry about whether my mask is going to work. I know too many people who have screwed their health in one way or another due to exposure to stuff that they were ignorant could harm them. But that's me, other people will approach things differently.
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