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Only information I have on this is from the Inquisitor RPG, wit the Navigator archetype. Under the archetypes powers (page 66 of the 2004 Inq. Annaul, or somewhere in the .pdf that's floating around the net) it lists one named 'The Lidless Stare' which, and I quote;
"The Navigator can stare deep into the soul of a single character..."
Because their eye is a direct connection with the Warp, I'd imagine that, as b-man states simply & directly to the point, only something with a soul, a connection to the Warp, can be affected by the third eye.
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