Pretty much the same way you did before, not a whole lot has changed in that regard, it'll just be harder. Lots of plasma or overwhelming 2+ sv's with lots of wounds will do it.
Tarpit the super killy units with lots of anti-chaos rules (e.g. Deathwing Knights) with culists and/or shoot them to death at range, get stuck in against everything else and make that cheap Veterans of the Long War work for you, and bring lots of Heldrakes.
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