No, no drybrush. You definitely don't want the dark hues on the edges around the light source. That will completely destroy the effect you're trying to get. You want a glow, with a transition from super bright light source through to your base tone.
You can achieve fairly easy glowing runes that look good without too much effort. What you need to do is take your base colour (make sure it's at it's darkest, add black if you can, you want the area with the runes to be dark as possible). Now add some base hue with some of the light hue mixed in. Apply this in a patch around the rune, I'd say about half a mil or so for the termie runes. You probably want to work a few layers to form a smooth patch of brighter tone around the rune. From there, work down to your glowing hue gradually, applying the layers in decreasing area over the rune. Once you've got a nice patch of tesseract over the rune, do a pin wash of white in the rune recess. Now from here you can just leave it, or work it back and forward a bit more with white mixed into the tesseract to smooth it off. Remember, the centre of the rune needs to be super bright.
Sure, this way will take a little more effort, but it will looks far better than drybrushing.
I've recently just used this method on my Horus ascended with a fire glow over black, but unfortunately the photos are all focused on his head so don't show it well. I've attached a photo of Abaddon that I painted about 4 years back, you can sort of see this effect over the runes on his legs.
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