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So this came up in a game against Custodes. The game was ultimately a loss, but this tactical nugget emerged.

My opponent pointed out that one custodes blob sitting on an objective had access to 'fights first'.
I charged a lone assasin instead, but in such a fashion that on the pile in move, I could pile into that fights first unit. My opponent couldn't activate the unit until I had activated mine because he wasn't in engagement range until after I activated. Thus I circumvented fights first.

If an opponent has a unit without fights first near a unit with fights first, you might similarly be able to circumvent fights first by charging the first unit and piling into the second. Put it in your toolbox. And if you're running units that fight first, Think of this case before putting them right next to other units that don't.

That's rather hard to do. You must go into b2b if you can and once in b2b can't pile in

Best chance for that is when you are more than 7, less than 8 and even then just 1/6 chance of pulling it up. roll 6 or less, charge fails, roll 8+, must go to b2b and can't pile in.