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Two words make any gene seed mutations shenanigans plausible in fluff. Cursed Founding.

I mean that's one instance of a widespread, unsanctioned space marine founding. Who's to say that there haven't been other chapter founded in secrecy. Or other chapters with major mutations that we don't know about.

I'm now writing fluff for it and will post it when I get the founding finished.

I thought of possesed CSM, but instead of demon mutations, it had tyranid mutations when I first read it.