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An interesting situation came up the other day: A squad of Deathcult Assassins and an Inquisitor were locked in combat with one of my Talos (Taloses...Talosi?). I assaulted them with a squad of Wyches. The Inquisitor had a couple of those grenades with the "may be used if assaulting or if assaulted" stipulation.

Neither of us knew if those grenades could be used by units that were already locked in combat when assaulted. Defensive grenades can't, so that's the precedent we went with (just to keep the game going), but has there been a ruling on this one way or the other? Or maybe a similar situation with a grenade option from another codex?

those grenades can still be used.

you were assaulted by another unit, already being locked in combat isn't stipulated in the use of those grenades so it has no effect.

AS above. He still throws grenades in your direction.