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I've always had workshop space to airbrush, but I'd like to try airbrushing in my home office. If I am using solely acrylics and working in a four sided hood, what are the implications in terms of paint settling on the rest of my office and ventilation requirements? To be clear, this is miniature airbrushing, noy spray paint.

Thanks in advance.

I airbrush indoors. Generally not a problem, BUT:

1) The painting isn't so much an issue - yeah it throws up a little particulate, but if you're not sucking it in (and have a suitable catching area / dirty room) it won't cause too much of an issue. See points 4 and 5 though.

2) Your cleaning solvent (usually some form of Cellulose Thinner / MEK) is BAD TO BREATHE. You will need to vent the room after this, and don't hang round till the vapour well and truly dissipates. Headaches, nausea and giddiness will follow you if you don't.

3) Certain paints / thinners are also not great to breathe. Extensive work with Tamiya puts a lot of iso-alcohol in the air. It can give you a blinding headache.

4) Take regular breath breaks. Clean (flush) the brush, let the room vent a bit (LEAVE!), take a short walk outside to clear your lungs.

5) Wear a mask if doing longer sessions. Cheap filter masks won't catch all the particulate (respirators are for that) but they will help a bit.

If painting indoors, I suggest getting your self a paint booth. The one I favor the most for people who have not a lot of room is the Paasche HOBBY PAINT SPRAY BOOTH available at TCP Global. Of course, you can also make your own.
I don't own one myself but if I ever get the funds to buy one, I will. There were a lot of good reviews and I like the format and the price.
To add to that booth, if you can vent the air outside it's even better.