What I was saying is for 3D printing it's essential that your model is a completely closed solid, the normals (the way a polygon's 'facing') of your solids are all correct ie facing outwards, you don't have polygons and control points cutting through each other, etc etc. It avoids confusing the software that converts the model to the printing process and will save you a lot of time and headaches later on down the line. Likewise if you're taking a model from Max to Zbrush for some organic sculpting, a 'clean' mesh would be all 4-sided polygons which helps a lot when you're subdividing your model to add detail.
Apologies for the technical terms