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Chaos lord with Mark of Khorne, Juggernaut, Axe of Blind Fury, VotLW (150)
5 Spawn (150)
Helldrake (170)
10 Chaos Space Marines missle launcher, Plasmagun. Champion has Power weapon and combi-plas (195)
15 chaos marines with bolt pistol and CCW. Mark of Khorne, Veterans of the Long War. Champion has powerfist (265)
10 cultists (50)
Maulerfiend (125)
Vindicator with Seige Shield and combi-bolter

10 points left. Do I give the lord a roll on the rewards table, the 10 man squad VotLW, some guns for the cultists, or something else?
The plan is for the lord and the spawn to move up and start wrecking things. the Vindicator moves into a good spot to blast things with the demolisher cannon with some protection from the 10 man CSM squad. The 15 man squad advances behind the Maulerfiend and assaults whatever they have an opportunity to. The Helldrake goes after fliers and anything on the ground that has power armor. The cultists hide and try to claim an objective.
Any thoughts or suggestions?

Looks good.
The minor tweak I would make is to switch the cultists for marines with a plasmagun, you could get the points by cutting the power glove from the 15CSM unit and losing a marine from it.

If you're running into a gunline, your lord should make it but I wouldn't have expected many of the spawn to; particularly if facing a vindicator or broadsides. Unless backing up the lord and spawn the maulerfiend may get crack-bombed to pieces or stuck in and overly long combat

If you're sticking with the cultists get them some rifles.

Looks very good.

Good list, however I would drop the cultists and maybe give the 10 man marine squad a rhino and havoc launcher.. Will still leave you 13 points to spend (inc the 10 U had to start with.) and if you are dead set on those cultists drop the power fist and votlw from the 15 man squad and U will have enough points left to get them.

Drop the power fist from the Fauxzerker champion and give your lord a Sigil of corruption. 4+ invul is better than a powerfist on a champion that will probably die before he can use it in a challenge anyway. Then on top of that give him the gift of Mutation.