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It usually depends on the enemy list, but it also depends on the platform you want to put them on.
Razorwings do really well with disintegrators as they're usually flying around harassing infantry or light armor (but you'll probably want lances if you want them to be air superiority or back-up anti-tank). With Raiders, I usually leave the lance since popping an enemy transport and throwing poison the riders is fun. Ravagers can be easily tailored to your enemy much better, though, as they can take up to 3 of either weapon.
So, yeah. Disintegrators are good weapons, but the lance will usually win out since it can be easier to drown softer targets in poison shots/haywire.
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