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The best solution is to vent out of the house, using an actual exhaust vent, like your dryer or bathroom fan. A contractor can build one really easily.
This is not a replacement for a respirator, though. Unless you spray in a separated space (like a fume hood), you'll still get some particulates. I have a N95 respirator, and even with a hood, you can see the filters are discolored with paint.
Some paints like VMA are supposed to be safe. Others may have toxic resin, or a respiratory irritant. However, the polyurethane primers are what I worry about most as polyurethane is a carcinogen.
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