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I want to pick up the whole line of this stuff for airbrush work, since as a noobie to this stuff, i find manual thinning a huge headache to get right... I also plan to use this stuff for paintbushing needs too, is there any disadvantage when paint brushing brushing this stuff onto minis vs the regular model color line? Obviouly its thinner, but since its generally always a bad idea to use the regular stuff non thinned, does it really matter? I had someone tell me its not as easy to mix colours using this stuff...is there any truth to that? (i cant see why there would be.)

Mixing shouldn't pose any problems. They're perfectly suited to 'hairy stick' brushing, so long as you're accustomed (or willing to become so) to working with thinned paints. The only downside is that thinning works in one direction - you can't easily thicken them up for those tasks for which you might want a thicker paint.

Believe me, there are time where you would want thicker paint. The 'always thin' mantra is akin to the science you were taught in middle school - it's mostly BS (and that's not 'ballistic skill'), when you really get down to it, due to gross generalization, omitted exceptions, and a general 'dumbing down' of complicated topics. It's also the only functional understanding that you can instill in someone that doesn't already have a higher level of experience and knowledge about that and related topics, so it has its place.

[edit: typo]

Shouldn't be an issue, I use VMA 60:40 with GW overall (as in, most of my paints are VMA). They mix with each other fine, go on fine and basically have no issues.

I actually prefer to use the Model Air paints to the regular because it's pre-thinned and that's nice. The only issue I see when mixing the air paints with regular colours is that it will make it thicker, but that's not that bad, just add a little water

I use VMA paints with regular brushes as well. Works great. Just keep in mind that many VMA paints are not very opaque and therefore work best on white primer.

Also, consider looking at Vallejo Game Air. Same color quality as VMA, but a more tabletop compatible color palette.