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Reign in Hell has a solo play supplement that is free to download, but they (Adam Loper and Vince Venturella) came onto their own after that. They're making solo games with co-op and PvP modes instead of the usual other way around.

I've enjoyed Space Station Zero and expect the same from Deth Wizards.
Majestic 13 is probably great, but not a theme I'm interested in personally.