I ran a sniper character and it is simply downright the easiest of any builds to play as, it simply requires 3 things.
1.A Fethload of caps
2. The Perk Jury Rigging
3. 100 guns skill
you wont get these till mid game, but after that its A) super fun and B) a walk in the park. I went through deathclaw promonitory (I doubt some of you guys even know where that is!) with nothing but a single stealthboy (to actually get into the darn place) and a Anti-Materiel rifle with
AP rounds.
Jury rigging allows you to repair
AM rifles with varmint rifles, which are 100 caps each, so cheap as chips. This means your snipe is always in full condition.
100 gunskill means no sway on the sniper rifle scope, allowing for insanely long range shots, always sneak attacks and always critical hits. Killing deathclaws was never easier!
the fethload of caps is for actually aquiring a
AM rifle, or silenced sniper rifle failing that, and the required ammo. .50 BMG aint cheap, incendiary is even worse, but
AP is the way to go. Silenced Sniper Rifles are also great, allowing you to kill people and take their high level gear without getting faction hate. I went through almost all of Nellis Airforce Base killing them for their grenade launchers without a single one spotting me!
If your running a combat character, its a good idea to get the hockey mask, and chainsaws are a blast
Also theres these boxing gloves that put enemies to sleep (350 fatigue per hit I think). Those can be a lot of fun