Hmm, iifc, the original Rogue Trader back in the late 80s stated that the Abhumans were all the results of humans who got stranded on far flung worlds from humanity's earlier space expansion. During their times there, they either were mutated by warp radiations or genetically altered for better survival on certain worlds. Both Ogryns and Squats were the results of heavy gravity/extreme environment worlds, while Ratlings and Beastmen were more likely caused by warp radiations. But, hey, its been a long time since I've read that book..
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