I play Escher mostly, but my strategy may apply to you as well...basically, I shift gear around on my gangers based on how each one advances skill/stat-wise. So, if I end up getting a
WS boost on someone, I'll generally throw some
CC weapons on them. If they get a
BS bonus I'll give them a lasgun...generally the lasgun is the better option, it is more reliable than the autogun due to its lower ammo-roll stat. I cant remember, it may have a range advantage as well.
I know that Escher tend to have more
CC skills available than the Delaque, but I think the strategy I explained above is still valid with any gang...you are going to get into
CC sooner or later, and you should have it be on your terms (ie send a ganger armed and 'trained' for it.
You mentioned you are going to scratch build your models, but I just got my order of trenchcoat gangers from Heresy Miniatures in the
UK ( I see that you are form there as well, so shipping and price may be better for you than it was for me.) If you haven't seen the models, definitely check them out!
http://heresyminiatures.com/shop/index.php?main_page=index&cPath=2_15