In the 40k universe, the smartest, most supernaturally gifted man to ever exist tried his hand at genetic manipulation, and his efforts degenerated into vampires, werewolves, dragon-men, and pissed-off narcoleptics. This is frickin' 40k we're talking about-- try to get a nosejob and you're liable to end up with some kind of writhing tentacle in the middle of your face.
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