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Picked up a start collecting box for my entry into AoS, still pretty new to the rules and game. I have:
1 Chaos Lord - Chaos Runeblade, General
1 Chaos Lord - Daemon Weapon
1 Sorcerer - Crown of Conquest
5 Chaos Knights - Glaives
10 Warriors - 2x hand weapons
10 Marauder Horsemen - Javelins
1 Chariot - Flail

Went up against a flesheaters courts army and got totally wrecked without even killing a model. It has
1 Ghoul King
1 Varghulf - 1 shot my chariot
1 Terrorgheist - this thing 1 shot my general, all the knights and my 2nd lord all in 4 turns
3 Crypt Horrors
20 Ghouls

Having some major problems getting wounds on anything because they have armor then a 5+ ignore wound after that, then regeneration on top and their multi damage hits or mortal wounding hits just shreds through my multi wound models

I put a few wounds on the horrors but those got all healed up next turn. Put a few on the varghulf, also healed up. Terrorgheist just gets charged straight down my army with it's huge movement and able to hit whatever it wants, have a strong armor save, the secondary save then regen wounds after that making it basically unkillable.

What am I supposed to do?

Well.. don't do a few wounds on this, a few wounds on that ... just focus units and kill them. It's almost always the best thing to do considering healing and bravery tests.. but seems especially usefull against this army

Apart from that I do not know the rules for these troops well enough to give more specific advice.

It's pretty hard to focus on anything else than the Terrorgheist who flies 14" then charges whatever he wants before all of my units which are slower can maneuver to another target, so its either pile in to try to kill this 4+ save, then 5+ save then regen on a 14 wound monster or leave that unit for dead

The rest of his units just follow and support the terrorgheist. Everything I have is melee and can't pile in enough units to bring this down. Turn 2 and on the rest of his units come in to support

You have a lot of solid main line units/characters but nothing else. There's no real support, tricky stuff, heavy hitters, anvils, etc. Or in other words, everything you have is more or less well-rounded (in melee terms) but that means the army isn't actually good at anything. So as for improving it...

-Drop the Chaos Warriors or the Chaos Knights. They give you 4+ save models with decent attacks but no rend, which you already have too much of. If you keep the knights swap their glaives for ensorcelled weapons, they'll be worse on the charge but every other combat you'll be glad you switched.

-Make the chariot the exalted charioteer if you didn't already and give him a chaos great blade instead of the flail.

-Split the Marauder Horsemen into two units and put them on opposite flanks or even just run one unit of 5. Send them to capture/contest objectives, help focus on stuff you are about to hit in melee,, and generally be annoying. Make him send his units away from the main line if he wants to kill them. Sidenote; these guys will almost certainly die at some point, that's ok.

-Focus your attacks, he may heal but its only d3 and only in his hero phase. Avoid focusing on the units unless the varghulf is dead.

-Bring some Chosen, they'll chop up stuff and potentially buff your other units when they do.

-Go with mark of Khorne or Nurgle on your general and troop units for re-rolls of hit or wound of 1.

Yeah army feels a bit fragmented with the knights, chariot and horsemen being faster than all the heroes and horsemen got caught out. I'll split them into 2 units of 5 and keep some distance.

Will change the flail and glaives to weapons too