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A few general thing that are good VS custode (Note: I play custodes).

Str 5/6 weapons with AP-1/2

Any more is a waste so getting lots of shots at that kind of profile is great - assault cannons, shuriken cannons and the like are pretty efficient.

Anything with 3 flat damage, thunder hammers or Helverin autocannons are perfect.

Anything with damage reduction - custodes mainly deal a flat 2 damage, especially in combat, so dreads or deathguard with -1 damage are very good against them.

Custodes put out lots of quality attacks so invuln saves and transhuman/hitsman effects are powerful against them.