Dante. Hands down.
That is, if you only include as Astartes the space marines that remained loyal forever. And Adeptus Astartes are defined by their loyalty and service to the Imperium.
If you include non-Astartes space marines (as in: humans augmented in this certain way, loyalties be damned) then it would have to be Erebus. While he was most likely just a puppet, he was in a pivotal position, all things considered.
Of course, the only thing that really matters if how well the Astartes work as a whole. There's bound to be peaks but they don't matter that much in the grand scheme of things.
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