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2014/10/10 13:00:27
Subject: Important member information
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[DCM]
Et In Arcadia Ego
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link
Laboratory-Grown Penises Ready To Be Tested In Humans
Scientists at the Wake Forest Institute for Regenerative Medicine could be offering new hope to men with genital abnormalities or injuries in as little as five years, thanks to one of their many tissue engineering endeavors: lab-grown penises.
While that may sound a little far-out, these guys are among the world leaders in regenerative medicine and they’ve achieved some remarkable things in the past. Back in 1999, they became the first in the world to successfully implant a lab-grown organ into humans—a bladder. Since then, they’ve transplanted engineered vaginas into women born with defects or without vaginas entirely, and have started working on growing tissues and organs for more than 30 different areas of the body.
Team leader Anthony Atala began this genital journey back in 1992, but it was not until 2008 that the scientists proved transplanting engineered penises was theoretically possible. Having spent a considerable amount of time working out the best way to engineer these tricky organs, the team managed to grow 12 functioning penises for rabbit subjects. After grafting them on to the recipients, all tried to mate with a female, eight successfully ejaculated, and four produced offspring. While these results were certainly encouraging, gaining approval for human trials is another kettle of fish. However, Atala is confident that it could be granted by the FDA within five years if they can prove the technique is safe.
So how do they do it? They first obtain a donor penis and strip all the cells from it with a detergent. The researchers are then left with a collagen scaffold which they then seed with a combination of cultivated smooth muscle and endothelial cells from the recipient. Using the patient's own cells eliminates the risk of immunological rejection that often occurs when transplants are given from another individual. However, because the cells are taken from the male’s genitals, it means that the procedure could not be used for female-to-male sex reassignment surgery.
The team has already engineered six human penises that are ready for transplantation; if approval for trials is granted and they prove to be a success, the researchers hope that they could be used all over the world to help people with a variety of problems. In particular, they envisage them being used in men who have suffered from traumatic injuries, for example those returning from the battlefield. However, they could also be used in individuals with congenital abnormalities, or children born with a disorder known as ambiguous genitalia. In the majority of instances, boys born with this condition are given a sex-change at birth, which can lead to serious psychological problems throughout life.
This technique also offers a vast improvement from existing penis replacement options, which are far from ideal. The procedure involves constructing a penis from thigh or forearm tissue and then inserting a prosthetic inside in order to achieve sexual function. The prosthetic is either a permanently rigid rod that is difficult to conceal, or an inflatable rod that requires a pump.
Although the team is hoping to be able to replace entire penises when they initiate trials, they think that a more realistic goal is to start with partial replacements, for example helping patients with erectile dysfunction.
.. Bonus points for saying they'll be tested " in humans" .
Bit concerned over " They first obtain a donor penis " which one would imagine would perhaps involve a bit more than a sit down and or a sugary drink/cookie afterwards if you're the donor.
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The poor man really has a stake in the country. The rich man hasn't; he can go away to New Guinea in a yacht. The poor have sometimes objected to being governed badly; the rich have always objected to being governed at all
We love our superheroes because they refuse to give up on us. We can analyze them out of existence, kill them, ban them, mock them, and still they return, patiently reminding us of who we are and what we wish we could be.
"the play's the thing wherein I'll catch the conscience of the king,
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2014/10/10 13:14:10
Subject: Important member information
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Decrepit Dakkanaut
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It's a trap!
Literally.
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2014/10/10 13:18:48
Subject: Important member information
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Longtime Dakkanaut
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Laughed really hard at that thread title. Bravo.
On topic, this is pretty awesome. I can't imagine the self esteem issues that must come along with losing your junk. Being able to fix the damage or defect will probably go a long way in helping those people feel better about themselves.
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2014/10/10 13:22:10
Subject: Important member information
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Last Remaining Whole C'Tan
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 reds8n wrote:Team leader Anthony Atala began this genital journey
I've got that dvd
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 lord_blackfang wrote:Respect to the guy who subscribed just to post a massive ASCII dong in the chat and immediately get banned.
 Flinty wrote:The benefit of slate is that its.actually a.rock with rock like properties. The downside is that it's a rock
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2014/10/10 13:22:37
Subject: Important member information
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Decrepit Dakkanaut
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Would have been funny if the article didn't directly address the fact that this is not an option.
But can it be used to upgrade?
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2014/10/10 13:25:03
Subject: Re:Important member information
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Ultramarine Librarian with Freaky Familiar
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Do they come in different sizes?
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2014/10/10 13:26:55
Subject: Re:Important member information
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[DCM]
Et In Arcadia Ego
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the team managed to grow 12 functioning penises for rabbit subjects.
.. and you thought they shagged a lot before !
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The poor man really has a stake in the country. The rich man hasn't; he can go away to New Guinea in a yacht. The poor have sometimes objected to being governed badly; the rich have always objected to being governed at all
We love our superheroes because they refuse to give up on us. We can analyze them out of existence, kill them, ban them, mock them, and still they return, patiently reminding us of who we are and what we wish we could be.
"the play's the thing wherein I'll catch the conscience of the king,
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2014/10/10 13:31:26
Subject: Re:Important member information
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Ultramarine Librarian with Freaky Familiar
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reds8n wrote: the team managed to grow 12 functioning penises for rabbit subjects.
.. and you thought they shagged a lot before !
My god...what have they done?! 
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2014/10/10 13:34:02
Subject: Re:Important member information
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Longtime Dakkanaut
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This may make me reconsider being an organ donor...
I like the idea of my penis outliving me...echoing in eternity...
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This message was edited 1 time. Last update was at 2014/10/10 13:35:56
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2014/10/10 13:48:31
Subject: Re:Important member information
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Contagious Dreadnought of Nurgle
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 NuggzTheNinja wrote:This may make me reconsider being an organ donor...
I like the idea of my penis outliving me...echoing in eternity...
Call me selfish, but I'd quite like to be buried with my old chap. We've been together forever....
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2014/10/10 14:00:48
Subject: Important member information
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Oberstleutnant
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The 5 assed monkey better watch out.
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This message was edited 1 time. Last update was at 2014/10/10 14:00:57
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2014/10/10 14:02:01
Subject: Re:Important member information
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[DCM]
Et In Arcadia Ego
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NuggzTheNinja wrote:This may make me reconsider being an organ donor...
I like the idea of my penis outliving me...echoing in eternity...
One wonders if one could perhaps leave it in a will, to be passed on down through the generations....
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The poor man really has a stake in the country. The rich man hasn't; he can go away to New Guinea in a yacht. The poor have sometimes objected to being governed badly; the rich have always objected to being governed at all
We love our superheroes because they refuse to give up on us. We can analyze them out of existence, kill them, ban them, mock them, and still they return, patiently reminding us of who we are and what we wish we could be.
"the play's the thing wherein I'll catch the conscience of the king,
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2014/10/10 14:06:22
Subject: Re:Important member information
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Last Remaining Whole C'Tan
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Plus, in like-new condition, would be a waste to toss it out, right? Hyeh hyeh.
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lord_blackfang wrote:Respect to the guy who subscribed just to post a massive ASCII dong in the chat and immediately get banned.
Flinty wrote:The benefit of slate is that its.actually a.rock with rock like properties. The downside is that it's a rock
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2014/10/10 14:10:46
Subject: Re:Important member information
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Contagious Dreadnought of Nurgle
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 Ouze wrote:Plus, in like-new condition, would be a waste to toss it out, right? Hyeh hyeh.
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2014/10/10 14:35:39
Subject: Important member information
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Decrepit Dakkanaut
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Wow... being posted by a Mod, I honestly thought this was going to be a thread regarding upcoming changes to AUP or user rules.
This is so much better!!
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2014/10/10 14:42:52
Subject: Re:Important member information
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5th God of Chaos! (Ho-hum)
Curb stomping in the Eye of Terror!
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Kinda puts the phrase:
I wouldn't  him/her with a borrowed , in different light... no?
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Live Ork, Be Ork. or D'Ork!
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2014/10/10 17:22:48
Subject: Important member information
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Androgynous Daemon Prince of Slaanesh
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At first I found the article in poor taste. But it's starting to grow on me.
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Reality is a nice place to visit, but I'd hate to live there.
Manchu wrote:I'm a Catholic. We eat our God.
Due to work, I can usually only ship any sales or trades out on Saturday morning. Please trade/purchase with this in mind. |
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2014/10/10 19:14:58
Subject: Re:Important member information
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[DCM]
The Main Man
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Ouze wrote:Plus, in like-new condition, would be a waste to toss it out, right? Hyeh hyeh.
That is literally one of the sickest burns I've ever witnessed on Dakka.
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2014/10/10 19:23:15
Subject: Important member information
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Kid_Kyoto
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I refuse to take your contribution on face value.
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2014/10/10 20:05:37
Subject: Important member information
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Legendary Master of the Chapter
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Oh come on. This is your chance to be the bigger man.
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2014/10/10 20:07:24
Subject: Important member information
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Battlefield Tourist
MN (Currently in WY)
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"I'm not just the president, I'm also a client."
-Sy Sperling, Hair Club for Men
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Support Blood and Spectacles Publishing:
https://www.patreon.com/Bloodandspectaclespublishing |
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2014/10/10 20:51:56
Subject: Re:Important member information
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Decrepit Dakkanaut
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They mention payment plans yet?
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Proud Member of the Infidels of OIF/OEF
No longer defending the US Military or US Gov't. Just going to ""**feed into your fears**"" with Duffel Blog 
Did not fight my way up on top the food chain to become a Vegan...
Warning: Stupid Allergy
Once you pull the pin, Mr. Grenade is no longer your friend
DE 6700
Harlequin 2500
RIP Muhammad Ali.
Jihadin, Scorched Earth 791. Leader of the Pork Eating Crusader. Alpha
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2014/10/10 20:54:51
Subject: Important member information
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The Conquerer
Waiting for my shill money from Spiral Arm Studios
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I'll take the footlong Italian please. Extra meat.
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Self-proclaimed evil Cat-person. Dues Ex Felines
Cato Sicarius, after force feeding Captain Ventris a copy of the Codex Astartes for having the audacity to play Deathwatch, chokes to death on his own D-baggery after finding Calgar assembling his new Eldar army.
MURICA!!! IN SPESS!!! |
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2014/10/10 20:55:24
Subject: Important member information
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Kid_Kyoto
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BobtheInquisitor wrote:
Oh come on. This is your chance to be the bigger man.
Well played, sir.
Jihadin wrote:They mention payment plans yet?
Heh, can you imagine if someone stiffed them?
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This message was edited 1 time. Last update was at 2014/10/10 20:55:42
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2014/10/10 20:55:47
Subject: Important member information
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Decrepit Dakkanaut
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Five Dullah Foot LLOOONNGGGG special
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Proud Member of the Infidels of OIF/OEF
No longer defending the US Military or US Gov't. Just going to ""**feed into your fears**"" with Duffel Blog
Did not fight my way up on top the food chain to become a Vegan...
Warning: Stupid Allergy
Once you pull the pin, Mr. Grenade is no longer your friend
DE 6700
Harlequin 2500
RIP Muhammad Ali.
Jihadin, Scorched Earth 791. Leader of the Pork Eating Crusader. Alpha
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2014/10/10 20:59:07
Subject: Important member information
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The Conquerer
Waiting for my shill money from Spiral Arm Studios
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 daedalus wrote:
Jihadin wrote:They mention payment plans yet?
Heh, can you imagine if someone stiffed them?
I believe that's what they're doing to their customers. 
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Self-proclaimed evil Cat-person. Dues Ex Felines
Cato Sicarius, after force feeding Captain Ventris a copy of the Codex Astartes for having the audacity to play Deathwatch, chokes to death on his own D-baggery after finding Calgar assembling his new Eldar army.
MURICA!!! IN SPESS!!! |
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2014/10/10 21:12:29
Subject: Re:Important member information
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Member of the Ethereal Council
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I hope they where not using human ppenises.
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2014/10/10 21:17:46
Subject: Re:Important member information
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Kid_Kyoto
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I just had a Dickwolves flashback.
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2014/10/10 21:28:39
Subject: Important member information
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Ragin' Ork Dreadnought
Monarchy of TBD
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Is there an exalt thread button? This one goes to 11!
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Klawz-Ramming is a subset of citrus fruit?
Gwar- "And everyone wants a bigger Spleen!"
Mercurial wrote:
I admire your aplomb and instate you as Baron of the Seas and Lord Marshall of Privateers.
Orkeosaurus wrote:Star Trek also said we'd have X-Wings by now. We all see how that prediction turned out.
Orkeosaurus, on homophobia, the nature of homosexuality, and the greatness of George Takei.
English doesn't borrow from other languages. It follows them down dark alleyways and mugs them for loose grammar.
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2014/10/10 21:36:15
Subject: Re:Important member information
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Dakka Veteran
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I was expecting that the ah, replacement parts, were being grown on lab mice. Like masts on a ship
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5000pts 
6000pts 
3000pts
