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https://www.livescience.com/monkeys-cannot-get-reinfected-with-coronavirus-study.html

A small study suggesting that there is an effective immune response once recovered. it has limitations in the small size and quick re-test period. I guess the question is more, how long does the immunity last?

 queen_annes_revenge wrote:
Is there anything concrete saying that they don't? an educated assumption would assume that the effective antibodies will remain, at least for a short period.

Apart from studies not showing much if any? Plus better to assume this corona is like previous corona virus unless evidence points otherwise. Previous corona viruses haven"t given much of longterm immunity. And being 4-8 weeks safe isn't much of help.

 queen_annes_revenge wrote:
https://www.livescience.com/monkeys-cannot-get-reinfected-with-coronavirus-study.html

A small study suggesting that there is an effective immune response once recovered. it has limitations in the small size and quick re-test period. I guess the question is more, how long does the immunity last?

compared to the munich cluster study which are actual humans compared to an Apebased study?

ehhh, i remain that it is more likely then not that Humans will not have longterm capability which makes Herdimmunity a pipedream

I'm inclined to agree, if you go off comparison to other coronas, but is it our immunity, or the virus mutating? Id like to hope that if the virus has to mutate like flu and the like, it will become (even) less deadly in the longer term.

 queen_annes_revenge wrote:
I'm inclined to agree, if you go off comparison to other coronas, but is it our immunity, or the virus mutating? Id like to hope that if the virus has to mutate like flu and the like, it will become (even) less deadly in the longer term.

Yes, if the virus mutates, which if it becomes seasonal it will, it will become less deadly as it adapts to the host species. Remember that the virus seeks only to reproduce, not to kill its allotted average number of humans per cycle.

As Off today borders between switzerland, Austria and Germany reopen.
Good for economy and transportation.

whirlwindstruggle wrote:

 queen_annes_revenge wrote:
I'm inclined to agree, if you go off comparison to other coronas, but is it our immunity, or the virus mutating? Id like to hope that if the virus has to mutate like flu and the like, it will become (even) less deadly in the longer term.

Yes, if the virus mutates, which if it becomes seasonal it will, it will become less deadly as it adapts to the host species. Remember that the virus seeks only to reproduce, not to kill its allotted average number of humans per cycle.

Virus mutation is entirely random, due to errors in the RNA replication process. You can't definitely say it will or won't mutate, or that it will or won't become less deadly as a result.

Not Online!!! wrote:


Allbeit the E thingy is probably even more funny considering how the fighters are treated

That's how I meant it, of course . Not a typo at all . No sirree.

Bran Dawri wrote:

Not Online!!! wrote:


Allbeit the E thingy is probably even more funny considering how the fighters are treated

That's how I meant it, of course . Not a typo at all . No sirree.

i am swiss, swiss german, my humor is entirly based upon sarcasm, dry brittle quips and agitation torwards other swiss germans.

jokes aside, that dude that owns WWE is a certified scumbag.

That's why I said I hope...


Automatically Appended Next Post:
https://www.independent.co.uk/news/uk/home-news/coronavirus-act-unlawful-prosecutions-review-uk-a9516566.html
Hmm..

https://twitter.com/Telegraph/status/1260949102617075712

A factory in Colombia is making hospital beds that can be turned into a coffin if the patient dies

These dual-purpose beds are designed for #COVID19 patients

Bloody hell eh ? Bet that'll do wonders for your morale, finally get into hospital, taken to the ward and then.... " we have a special bed for you" ...


what a time to be ali....oh, actually

https://www.sciencemag.org/news/2020/05/t-cells-found-covid-19-patients-bode-well-long-term-immunity#

While we're talking about immune system.. Study focused on t-cells rather than antibodies.

I wonder how long lasting and durable they are against water and spillage. Or even how comfortable and suitable they are as a bed. It just seems that you're laying on a cardbox sheet with a few supports underneath.

I get that during a crisis one can't be too picky, but at the same time I'd wager America should be able to mass produce something to a slightly higher degree of standard.


Then again I'm guessing they'll be for cheap export to poorer nations unable to afford better and potentially in greater need of convertible beds...

I read a study which said 0.4% of the population had been infected in the UK.

I've also read a study which said the evidence about antibodies seems to be that someone who gets a mild case develops fairly low resistance.

I remember as a boy I had German Measles three times over the course of a few years.

The scientists are still gathering data about this virus. It's rather early to make assumptions.

Regarding the "if" this virus mutates and adapts, that isn't an if. Moving a virus into a new host species changes the evolutionary immune system pressure on the virus -- which itself is mutable by dint of the poor error checking in an enzyme called a viral polymerase. Think of it as a xerox machine for nucleic acids (the genome) that however has random errors every time it makes a zerox. There are literally so many copies of a virus in an infected person that it becomes the old "infinite number of monkeys" typing -- and one or another of the slightly altered viruses codes for a different, but useful, protein. Perhaps it is more highly expressed, changing a balance between other cellular regulators. Perhaps it more closely resembles the human, rather than bat, cell wall protien and thus enables the virus to more effectively escape detection.
Point is, you are never going to look at a single virus, but a population of viruses, even in one person. Things that would be killed off by the immune systems of bats and pangolins manage to escape immune surveillance, and if they are truly better evolved for human reproduction they gradually (in not that many passes through human hosts) become more and more frequently found in the population of virus being spread.

Wow that is a big lump of text. I will read through that properly later as it does seem to be relevant info.

It is too early to speak in definites.. That's why I'm not doing so.

 reds8n wrote:
https://twitter.com/Telegraph/status/1260949102617075712

A factory in Colombia is making hospital beds that can be turned into a coffin if the patient dies

These dual-purpose beds are designed for #COVID19 patients

Bloody hell eh ? Bet that'll do wonders for your morale, finally get into hospital, taken to the ward and then.... " we have a special bed for you" ...

what a time to be ali....oh, actually

Yeah, thats a really bad idea.

Way more expensive then a bed and a normal coffin I'm sure. Bedside manner is an important part of medicine, but you toss that right out if the patient's are in a literal coffin.

This disease isn't dangerous enough that we need to burn everything that it contacted. This isn't a cheap SYFY drama. Besides, even if it was, you'd still need to throw the bed away if the patient survived. So you wasted the coffin part of the bed.

SAGE have revised the UK R-number back up. Based on data from three weeks ago.

https://abcnews.go.com/Health/coronavirus-reach-grave-deceased-body-transmits-covid-19/story?id=70144804

You know though, if one were inclined to overreact, and saw this report, I could see the coffin beds being authorized. As time has borne out, definitely not a major threat, but some outbreaks in the past have been made much worse by improper care of the deceased- I know ebola especially tends to spread while disposing of the bodies.

I've no knowledge of how sophisticated, or unsophisticated Colombia's medical service is, but this may have been someone thinking it was the best they could do with what they had available.Morbid, to be sure- but logical if you were intent on avoiding infection by the dead.

Ebola, as far as I'm casually aware, spread not specifically because of contact with the dead, but because of an almost total lack of hygiene practice and use of traditional body preparation methods that basically brought those treating the body into contact with a lot of bodily fluids. Basically the ideal situation for the Ebola to spread.

That's partly why it had such a dramatic effect in the countries it hit, but didn't really spread into the "western world" in any great manner. It spread through direct body fluid exchange/contact.

Ebola has never spread far into human societies because of how absurdly lethal it is.

It is a disease that exists in wild reservoirs that occasional jumps to humans only for it to inevitably burn itself out.

Indeed. It was an unfortunate issue with the local culture that resulted in the living contacting the dead's bodily fluids during the burial process.

Which is why Ebola was never ever a threat to the larger world. Any society that practices even century old hygiene practices would see little to no spread of Ebola.

 queen_annes_revenge wrote:
https://www.livescience.com/monkeys-cannot-get-reinfected-with-coronavirus-study.html

A small study suggesting that there is an effective immune response once recovered. it has limitations in the small size and quick re-test period. I guess the question is more, how long does the immunity last?

They've found wonder drugs for just about everything in one animal study or another, just to see the compounds fail spectacularly during human trials. That's why they do human trials. What you describe isn't clinical development, but the same logic applies.

As an aside, that's also why they do pediatric studies. Because children are not simply little adults. Drugs may have more or less efficacy in kids. It isn't intuitive.

The media tends to be AWFUL at reporting the results of studies, which is something people need to keep in mind during this time. It's crazy just how much these reporters get wrong and how often they get it wrong. We can be hopeful, but we need to take this stuff with that giant grain of salt meme pic.

I think a lot of the errors come not just from fact being turned into opinion; but also because a lot of news references each other - then makes it shorter. So when something gets re-written a dozen times and then cut in half a few more you can end up with minor facts getting highlighted; main facts getting missed out and the original meaning lost. Same as if you've ever played Chinese Whispers.

A pizza place here had the unfortunate timing of opening up just as the lockdown began. Somebody here said try to help the little businesses through this and I took that to heart. And I’m glad that I did because it was really good pizza.

In all seriousness think that there will be a bit of a boom when it’s safe to go back out in big numbers?

What is the average American feeling down there? Are people concerned? You can’t tell from US media because it’s so partisan. It seems like 100,000 deaths will be coming an about a week. Will that benchmark alarm people or are folks kind of over this whole Coronavirus virus thing?

That's one thing I'd like to hear the answer to as well. My psychology doesn't click with crisis* so I have no idea what a normal person feels like save hearing it from others.

*For mental health reasons.

 KamikazeCanuck wrote:
What is the average American feeling down there? Are people concerned? You can’t tell from US media because it’s so partisan. It seems like 100,000 deaths will be coming an about a week. Will that benchmark alarm people or are folks kind of over this whole Coronavirus virus thing?

People are concerned about their grandparents getting it, but a lot of people I've talked to aren't as concerned about themselves catching it. The feeling I've gotten talking to others is that they are ready for the quarantine to end for the country at large and that only hotspots/those most susceptible should be locked down at this point. The US is so large and varied that a blanket lockdown just isn't what is needed right now.

Edit: Personally, idk what the right choice is. If the lockdown ended it wouldn't scare me, but I'm also young and don't have any respiratory issues. The 100k benchmark will alarm people who are already alarmed by the disease, but I doubt it will alarm people who are ready for the lockdown to end.

 KamikazeCanuck wrote:
What is the average American feeling down there? Are people concerned? You can’t tell from US media because it’s so partisan. It seems like 100,000 deaths will be coming an about a week. Will that benchmark alarm people or are folks kind of over this whole Coronavirus virus thing?

Central Florida here.

It's really inconsistent. If you believe it is a serious matter, you're social distancing in public, and wearing a mask- my sons and I do, and there's a vague sense of unease on our rare trips out. That being said, you'll see masks in uniform use in some stores, but in most it's at best 1/3 of people wearing them, and many people have decided that the quarantine isn't worth doing. My jiujitsu gym started breaking it two weeks ago or so for people to wrestle each other. I didn't attend any of those practices- because I'm not invested enough to pick up a ticket for violating local ordnances. It'll officially be open Monday, and once it is then I'll probably start my son back up in it. Once he starts, my family's exposed to that gym's attendance, so we'll broaden from 1 family exposure to 15 or so families. Unlike my wife and I, he's extremely social, and the isolation is really wearing on him. My opinion is that the full lockdown can't hold- what you need to do now is find the smallest sustainable circle you can handle for the foreseeable future.

Heck, visiting my school all of the office staff and administrators had given up on masks, while the teachers who were there to clean out classrooms and drop off keys were masked. Opinions, and responses, vary wildly, but are trending towards acceptance, with or without precautions. Which is to be expected, considering our official response has been do your own thing.

That is natural. It's impossible for humans to maintain a heightened state of readiness for long periods of time, whether that's a single person, or an entire population. It's possible to 'surge' to paraphrase my boss' favourite buzzword, but not indefinitely.